A Near Haploid Clone: 24, XY, t (9; 22) (q34; q11) from a Patient in Blast Crisis of Chronic Myeloid Leukaemia
- 1 August 1978
- journal article
- research article
- Published by Wiley in Scandinavian Journal of Haematology
- Vol. 21 (2) , 99-103
- https://doi.org/10.1111/j.1600-0609.1978.tb02499.x
Abstract
Chromosome studies on bone marrow in a patient with chronic myeloid leukaemia (CML) revealed a mosaic picture with a dominant clone of 24, XY, t (9; 22) (q34; q11). This corresponded to a preponderance of minute blasts in smears of bone marrow aspirate. It is suggested that a haploidy event rather than progressive hypodiploid loss, is responsible for the genesis of the miniature blast cells.Keywords
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