Evaluation of reagin screen, a new serological test for syphilis

Abstract
Serum and plasma specimens (1020) were tested using the Venereal Disease Research Laboratory (VDRL), Rapid Plasma Reagin (RPR) card, Reagin Screen (RST) and Fluorescent Treponemal Antibody-Absorption (FTA-ABS) tests. In 257 normal patients all screening tests were nonreactive; the FTA-ABS test was reactive for 1 patient. In 588 patients with treated and untreated syphilis, the RST results were 91.7% in agreement with the VDRL and RPR results. In 175 patients with diseases that cause biological false reactions, the RST was 94% in agreement with the other screening tests. The titer of the RST was within 1 dilution of the corresponding VDRL titer in 91.75% of the 360 specimens tested and within 1 dilution of the RPR titer in 96.9% of 358 specimens quantitated by both tests.