Mitotic chromosome loss in a radiation-sensitive strain of the yeast Saccharomyces cerevisiae.
Open Access
- 1 September 1981
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 78 (9) , 5778-5782
- https://doi.org/10.1073/pnas.78.9.5778
Abstract
Cells of S. cerevisiae with mutations in the RAD52 gene are defective in meiotic and mitotic recombination, in sporulation, and in repair of radiation-induced damage to DNA. Diploid cells homozygous for rad52 lose chromosomes at high frequencies; these frequencies of loss can be increased by exposure of these cells to X-rays. In survivors of X-ray treatment chromosome loss events result in the conversion of diploid cells to cells with nearhaploid chromosome numbers.This publication has 27 references indexed in Scilit:
- A genetic study of the effects of the repair-deficient mei-9a mutation in drosophila on spontaneous and X-ray-induced paternal sex chromosome lossMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1981
- Genetic control of diploid recovery after γ-irradiation in the yeast Saccharomyces cerevisiaeMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1980
- Radiation-induced mitotic and meiotic aneuploidy in the yeast Saccharomyces cerevisiaeMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1979
- Genetic control of chromosome breakage and rejoining in Drosophila melanogaster: spontaneous chromosome aberrations in X-linked mutants defective in DNA metabolism.Proceedings of the National Academy of Sciences, 1979
- THE GENETIC CONTROL OF MEIOSISAnnual Review of Genetics, 1976
- Genetic characterization ofrec-1, a mutant ofUstilago maydisdefective in repair and recombinationGenetics Research, 1976
- The repair of double-strand breaks in the nuclear DNA of Saccharomyces cerevisiae and its genetic controlMolecular Genetics and Genomics, 1976
- A genetic study of X-ray sensitive mutants in yeastMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1974
- The tolerance of aneuploidy in yeastGenetics Research, 1970
- Studies of the genetic mechanism of radiation-induced mitotic segregation in yeastMolecular Genetics and Genomics, 1969