Cerebellar hypermetabolism in paraneoplastic cerebellar degeneration
- 1 April 2006
- journal article
- case report
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 77 (4) , 525-528
- https://doi.org/10.1136/jnnp.2005.075325
Abstract
A 51 year old man with paraneoplastic cerebellar degeneration from gastric adenocarcinoma showed cerebellar hypermetabolism and increased perfusion on brain FDG-PET scan and SPECT during the acute stage of his illness. The patient underwent subtotal gastrectomy. The intensity of the hypermetabolism had decreased markedly on follow-up FDG-PET 3 months later following two cycles of chemotherapy. We suggest that the cerebellar hypermetabolism may have been due to an acute inflammatory process associated with an immunological reaction.Keywords
This publication has 9 references indexed in Scilit:
- Serial 18F-fluoro-2-deoxy-D-glucose Positron Emission Tomography and Magnetic Resonance Imaging of Paraneoplastic Limbic EncephalitisArchives of Neurology, 2004
- Recommended diagnostic criteria for paraneoplastic neurological syndromesJournal of Neurology, Neurosurgery & Psychiatry, 2004
- Paraneoplastic cerebellar degeneration associated with antineuronal antibodies: analysis of 50 patientsBrain, 2003
- Anti-Yo-associated paraneoplastic cerebellar degeneration in a man with gastric adenocarcinomaJournal of the Neurological Sciences, 2001
- Limbic Encephalitis Investigated by18FDG-PET and 3D MRIJournal of Neuroimaging, 2001
- Paraneoplastic SyndromesArchives of Neurology, 1999
- Sequential MRI, SPECT and PET in respiratory syncytial virus encephalitisPediatric Radiology, 1999
- [Uncoupling of cerebellar blood flow and metabolism in paraneoplastic cerebellar degeneration: report of a case].1997
- Inflammatory infiltrates and complete absence of Purkinje cells in anti-Yo-associated paraneoplastic cerebellar degenerationActa Neuropathologica, 1996