Lack of Effect of Treatment for Helicobacter pylori on Symptoms of Nonulcer Dyspepsia
Open Access
- 1 October 1999
- journal article
- clinical trial
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 159 (19) , 2283-2288
- https://doi.org/10.1001/archinte.159.19.2283
Abstract
DYSPEPSIA IS an extremely common problem in the United States. A population-based study has suggested that as many as 25% of the population have symptoms consistent with dyspepsia.1 These symptoms include upper midabdominal discomfort or pain, nausea, early satiety, and abdominal bloating. Prior studies have demonstrated that dyspepsia is associated with peptic ulcer disease in approximately 20% of patients, gastroesophageal reflux disease in approximately 20% of patients, and gastric cancer in approximately 1% of patients.2,3 However, the majority of patients with dyspepsia have normal findings or only minor abnormalities on upper endoscopy and are therefore said to have nonulcer dyspepsia.This publication has 20 references indexed in Scilit:
- Eradication ofHelicobacter pylori and long-term outcome of functional dyspepsiaDigestive Diseases and Sciences, 1996
- Long-term prospective study ofHelicobacter pylori in nonulcer dyspepsiaDigestive Diseases and Sciences, 1995
- Empirical H2-blocker therapy or prompt endoscopy in management of dyspepsiaThe Lancet, 1994
- Bismuth subsalicylate suppression ofHelicobacter pylori in nonulcer dyspepsia: A double-blind placebo-controlled trialDigestive Diseases and Sciences, 1993
- Is Helicobacter pylori the cause of dyspepsia?BMJ, 1992
- Effect of colloidal bismuth subcitrate on symptoms and gastric histology in non-ulcer dyspepsia. A double blind placebo controlled study.Gut, 1990
- Campylobacter associated gastritis in patients with non-ulcer dyspepsia: a double blind placebo controlled trial with colloidal bismuth subcitrate.Gut, 1989
- Campylobacter pylori – A Role in Non-Ulcer Dyspepsia?Scandinavian Journal of Gastroenterology, 1989
- Non-ulcer dyspepsia and short term De-Nol therapy: a placebo controlled trial with particular reference to the role of Campylobacter pylori.Gut, 1988
- Campylobacter pyloridis and associated gastritis: investigator blind, placebo controlled trial of bismuth salicylate and erythromycin ethylsuccinate.BMJ, 1986