The Isolation of Defective Variants of Simian Virus 40 whose Genomes Contain Sequences Derived from Adenovirus 2 DNA
- 1 February 1978
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 38 (2) , 313-327
- https://doi.org/10.1099/0022-1317-38-2-313
Abstract
A new set of hybrid viruses was isolated whose closed circular genomes 5-6 kB [kile base] in size, contain DNA sequences derived in part from adenovirus 2 and in part from SV40. The structure of these genomes is complex, but in the simplest case, analyzes by [Eco RI, Hind III, Hpa I, Sma I, Hha I and Bgl I] restriction endonuclease digestion and hybridization indicate that the adenovirus 2 DNA is present as a continuous block, of maximum size 2.8 kB. Different hybrids contain sequences derived from different segments of the adenovirus 2 genome.This publication has 9 references indexed in Scilit:
- The arrangement of simian virus 40 sequences in the DNA of transformed cellsCell, 1976
- In situ hybridization of repetitive monkey genome sequences isolated from defective simian virus 40 DNACell, 1976
- Preparative isolation and mapping of adenovirus 2 early messenger RNA speciesJournal of Molecular Biology, 1976
- Amplification and characterization of a β-globin gene synthesized in vitroCell, 1976
- A specific endonuclease from Haemophilus haemolyticusJournal of Molecular Biology, 1976
- Enhancement of Adenovirus Growth in African Green Monkey Kidney Cell Cultures by SV40Experimental Biology and Medicine, 1964
- Biochemical studies on adenovirus multiplicationVirology, 1963
- Plaque production by the polyoma virusVirology, 1959
- Propagation in a Fluid Medium of a Human Epidermoid Carcinoma, Strain KBExperimental Biology and Medicine, 1955