Congenital hereditary retinoschisis: Evolution at the initial stage

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Abstract
Two male infants with congenital hereditary retinoschisis are presented. The disease was detected when they were 11 and 20 months old, respectively, and they were followed up during the subsequent months. Initially, they both revealed a tremendously elevated retinoschisis lesion in both equatorial and peripheral retina, which was associated with foveal retinoschisis. The peripheral ballooning retinoschisis regressed gradually in the following months, and a relatively flat retinoschisis was left. It was proposed that the early stage of the disease is characterized by a bullous retinoschisis followed by its spontaneous regression during the first several years of life. A survey of the literature favors our view.

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