Oral Contraceptives and Ovarian Cancer

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Abstract
To the Editor: Cramer et al. reported the results of a case–control study of ovarian cancer in women under the age of 60 years (Oct. 21 issue).1 They found, as had several other workers previously,2 3 4 5 6 7 8 that use of oral contraceptives was associated with a decreased risk of the disease. However, Cramer et al. reported that the decreased risk was evident only in women over 40 years of age, and that below this age oral-contraceptive use was actually associated with an increased risk of ovarian cancer. Since other workers had not broken down the data in this manner, Cramer et . . .