Assignment of two Japanese xeroderma pigmentosum patients to complementation group D and their characteristics.

  • 1 March 1985
    • journal article
    • Vol. 76  (3) , 162-6
Abstract
Japanese xeroderma pigmentosum sib patients XP58TO and XP59TO were assigned to complementation group D on the basis of cell hybridization studies. Ultraviolet and 4-nitroquinoline-1-oxide hypersensitivity and reduced unscheduled DNA synthesis of cells of these XP patients were also characteristic of authentic group-D cells. The patients have not yet developed either apparent neuromental abnormalities or skin cancers.

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