Ganglioside therapy for amyotrophic lateral sclerosis
- 1 August 1984
- journal article
- Published by Wolters Kluwer Health in Neurology
- Vol. 34 (8) , 1083
- https://doi.org/10.1212/wnl.34.8.1083
Abstract
A 6-month double-blind study of bovine brain gangliosides was carried out in 40 patients with ALS. Thirty-two patients completed the study; 18 were treated with gangliosides and 14 with placebo. Using 10 different objective tests of muscle strength, we failed to show a significant difference between the two groups in the progression of weakness. Daily intramuscular injections of 40 mg of brain gangliosides for 6 months had no beneficial effect in ALS.Keywords
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