Towards the Total Synthesis of Ambruticin: Preparation of the Fully Functionalised Right-Hand Portion Using the Intramolecular Silyl-Modified Sakurai (ISMS) Annulation
- 1 February 1996
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1996 (02) , 297-304
- https://doi.org/10.1055/s-1996-4185
Abstract
The concise synthesis of the fully functionalised right-hand dihydropyran subunit of the antifungal antibiotic ambruticin (1), using the ISMS annulation as the key-step, is described.Keywords
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