Abstract
Tryptic peptide mapping of fibronectin from various species indicates the following observations: there exists a remarkable similarity between methionine-labeled tryptic peptides of fibronectins isolated from cells of widely separated species such as human, chicken, mouse, hamster and rat; fibronectins from normal and transformed or tumor cells of the same species are very similar, if not identical; and collagen-binding regions of fibronectin from different species share identical major peptides.