Distinction of Serum Inhibitor of Activator-Induced Clot Lysis from 1-Antitrypsin
- 1 June 1974
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 146 (2) , 567-570
- https://doi.org/10.3181/00379727-146-38148
Abstract
Summary Antiactivator activity of human serum, which inhibits activator-induced clot lysis, was separated from α1-antitrypsin by affinity chromatography on Sepharose coupled with IgG of antiserum to α1-antitrypsin. It was found that most of antiplasmin activity formerly found in the antiactivator fraction is actually due to α1-antitrypsin contaminating the fraction. Antiactivator itself has no or little antiplasmin activity. On the other hand, α1-antitrypsin possesses antiplasmin activity but has no antiactivator activity.Keywords
This publication has 0 references indexed in Scilit: