THE BLOOD‐RETINAL BARRIER PERMEABILITY IN ESSENTIAL HYPERTENSION

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Abstract
In a series of 8 patients with recently discovered moderate essential hypertension the blood‐retinal barrier permeability to fluorescein was determined by aid of quantitative vitreous fluorophotometry before and after normalization of the systemic blood pressure. The permeability before medical treatment was 1.69·10‐7 cm/sec (± SEM = 0.14) and after medical treatment and normalization of the blood pressure 1.27·10‐7 cm/sec (± SEM = 0.12), corresponding to the permeability in a normal population. Thus the blood‐retinal barrier permeability is pathologically increased even in moderate degrees of essential hypertension, but this increase in permeability is reversible.