The in vitro and in vivo reaction at the N7-position of guanine of the ultimate carcinogen derived from benzo[a]pyrene
- 1 March 1979
- journal article
- research article
- Published by Elsevier in Chemico-Biological Interactions
- Vol. 24 (3) , 345-353
- https://doi.org/10.1016/0009-2797(79)90082-6
Abstract
No abstract availableThis publication has 13 references indexed in Scilit:
- The reaction of trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene with DNA involves attack at the N7-position of guanine moietiesChemico-Biological Interactions, 1977
- Benzo[a]pyrene diol epoxide covalently binds to deoxyguanosine and deoxyadenosine in DNANature, 1977
- Synthesis and reactions of the highly mutagenic 7,8-diol 9,10-epoxides of the carcinogen benzo[a]pyreneJournal of the American Chemical Society, 1977
- The reaction of (±)‐7α, 8β‐dihydroxy‐9β, 10β‐epoxy‐7,8,9,10‐tetrahydrobenzo(a)pyrene with dnaInternational Journal of Cancer, 1976
- Benzo[a]pyrene-nucleic acid derivative found in vivo: structure of a benzo[a]pyrenetetrahydrodiol epoxide-guanosine adductJournal of the American Chemical Society, 1976
- The reaction of 7,8-dihydro-7,8-dihydroxybenzo[a]pyrene-9,10-oxide with DNA in relation to the benzo[a]pyrene-DNA products isolated from cellsChemico-Biological Interactions, 1976
- Carbonium ion as ultimate carcinogen of polycyclic aromatic hydrocarbonsNature, 1975
- Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxideNature, 1974
- Metabolism and binding to cellular macromolecules of a series of hydrocarbons by mouse embryo cells in cultureInternational Journal of Cancer, 1969
- Molecular Mechanism of the Cytotoxic Action of Difunctional Alkylating Agents and of Resistance to this ActionNature, 1965