Gas chromatography with atomic absorption detection for the determination of alkyl selenide compounds in the breath of mice after administration of different selenium compounds
- 1 July 1983
- journal article
- research article
- Published by Taylor & Francis in Toxicological & Environmental Chemistry
- Vol. 6 (3) , 191-201
- https://doi.org/10.1080/02772248309357004
Abstract
Quantitative determination of dimethylselenide and dimethyldiselenide in the breath of mice after addition of different selenium compounds to the drinking water is described. Breath samples are collected with a cryogenic trap and analyzed by gas chromatography with atomic absorption spectrometric detection. Detection limits down to 0.2 ng/100 g body weight are obtained. The pulmonary excretion of selenium metabolites after oral administration via drinking water or after intraperitoneal injection appears to be negligible. The bioconversion of the different selenium species is discussed.Keywords
This publication has 30 references indexed in Scilit:
- Identification and determination of alkylselenide compounds in environmental airAtmospheric Environment (1967), 1983
- Determination of alkylselenide compounds in air by gas chromatography—atomic absorption spectrometryAnalytica Chimica Acta, 1982
- A simulation model describing the metabolism of inhaled and ingested selenium compoundsToxicology and Applied Pharmacology, 1981
- Factors Influencing the Inhibitory Effect of Selenium on Mice Inoculated with Ehrlich Ascites Tumor CellsScience, 1980
- Wholebody elimination of 75SeO32− and 203HgCl2 administered separately and simultaneously to miceToxicology, 1979
- Metabolic studies in rats of [75Se]selenomethionine and of 75Se incorporated in vivo into rabbit kidneyBritish Journal of Nutrition, 1975
- Metabolic studies with seleniated compounds—III. Lung excretion of selenium 75 and liver functionThe International Journal of Applied Radiation and Isotopes, 1968
- Metabolic studies with seleniated compoundsThe International Journal of Applied Radiation and Isotopes, 1967
- Selenium metabolismBiochimica et Biophysica Acta (BBA) - General Subjects, 1966
- Ueber Methylirung im ThierkörperNaunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1894