Histopathological Changes after Pseudophakos

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Abstract
Cataract extraction and iris clip lens implantation in an 88 yr old woman were followed by hyphema, anterior uveitis and organized exudates around the implant. The globe was enucleated after 15 mo. due to pain and poor visual prognosis. Sections showed an epithelial downgrowth into part of the anterior chamber, associated with a fibrous membrane which had surrounded part of 1 loop of the implant. Atrophy of the iris, adenomatous changes in a ciliary process and an after-cataractous ring were noted. Inflammatory changes were present in the uvea, associated posteriorly with degenerative choroido-retinitis, probably of arteriosclerotic origin. The nylon loops of the implant showed areas of biodegradation and were partly fibrosed in. The possible relationship of the various changes is discussed.

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