Myocarditis

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Abstract
THE historical evolution of concepts of primary diseases of the myocardium, including myocarditis, has recently been reviewed succinctly by Mattingly.1 Through careful post-mortem studies, Saphir2 called attention to the true autopsy incidence of inflammatory lesions of the myocardium, ranging from 3.4 to 9.3 per cent. Increased alertness on the part of clinicians led to many reports of myocardial involvement by systemic disease, and also to recognition of acute primary myocarditis, largely of unknown etiology.2 3 4 5 Only recently has it become possible to identify many of the latter as viral. Coxsackie viruses of Group B have been especially associated with myocarditis, with . . .