ROUTES OF CALCIUM MOVEMENT ACROSS THE CHICK CHORIOALLANTOIS
- 10 October 1976
- journal article
- research article
- Published by Wiley in Quarterly Journal of Experimental Physiology and Cognate Medical Sciences
- Vol. 61 (4) , 265-274
- https://doi.org/10.1113/expphysiol.1976.sp002358
Abstract
The mechanism of Ca transport across the chick chorioallantois was studied in vivo. The 15 day old membrane contains no Ca binding protein (CaBP); attempts to stimulate transport by adding this protein or vitamin D metabolites did not enhance the normal transport process. The mitochondrial and microsomal fractions of transporting cells contain only a small percentage of the 45Ca actually moved across the epithelium and simultaneous measurements of 45Ca and 3H inulin indicate that the bulk movement of fluid is not involved in Ca transport. Ca appears to be moved after being bound to a protein since Sr and PCMBS [p-chloromercuribenzene sulfonate] both interfere with transport and the membrane shows saturation kinetics. None of the existing theories seem to provide an adequate explanation for the mechanism of Ca transport. Some support is given to the possibility that intracellular routes are involved in part of the process.This publication has 1 reference indexed in Scilit:
- Physiological and ultrastructural aspects of ion movements across the chorioallantoisComparative Biochemistry and Physiology Part A: Physiology, 1976