Abstract
Administration of 250 μ g/ml NaF in drinking water to rats reduced both caries incidence (P < 0.001) and the percentage of S mutans (0.01 > P > 0.001) although the percentage of Actinobacillus sp. was increased (P < 0.001). An Actinobacillus sp. and S mutans FA1 both proliferated in NaF broth only if the NaF > 10 μ g/ml. which was associated with the inhibition of acid production.