The Arterially Perfused Enucleated Rabbit Eye as a Model for Studying Aqueous Humor Formation
- 1 January 1983
- journal article
- research article
- Published by S. Karger AG in Ophthalmic Research
- Vol. 15 (5) , 225-233
- https://doi.org/10.1159/000265264
Abstract
The rate of turnover of aqueous humor (Kout), as measured by the decay of radioactive inulin from the anterior chamber of the enucleated eye, was similar to the rate of loss of 125I-RISA (radioiodinated serum albumin) from the eye of a living rabbit. Arterial perfusion with 125I-RISA or rabbit serum showed that the permeability characteristics of the blood-aqueous barrier to protein molecules are unaffected in the enucleated eye. The viability of the enucleated eye for secretion of ascorbic acid was also examined, but the results were inconclusive.Keywords
This publication has 5 references indexed in Scilit:
- Blockade of the ocular effects of acetazolamide by phencyclidineExperimental Eye Research, 1977
- Studies on intraocular transport of taurine I. Accumulation in rabbit ciliary body-iris preparation in vitroBiochimica et Biophysica Acta (BBA) - General Subjects, 1968
- DIRECT OBSERVATION OF SECRETORY PUMPING INVITRO OF THE RABBIT EYE CILIARY PROCESSES - INFLUENCE OF ION MILIEU AND CARBONIC ANHYDRASE INHIBITION1964
- ACTIVE TRANSPORT OF ASCORBIC ACID IN ADRENAL CORTEX AND BRAIN CORTEX IN VITRO AND EFFECTS OFACTH AND STEROIDS1963
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951