Equilibrium binding of spermine and histamine to salmon sperm DNA and poly(dGdC)
- 1 November 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 40 (11) , 809-811
- https://doi.org/10.1111/j.2042-7158.1988.tb05179.x
Abstract
Studies using the solute-enhanced phase partition technique demonstrate that the endogenous amines histamine and spermine bind to both salmon sperm DNA and poly(dGdC) in a markedly cooperative fashion. Both compounds exhibited DNA sequence-dependence effects in their mode of binding. The linear aliphatic spermine molecule binds more strongly than histamine to both DNA types.This publication has 25 references indexed in Scilit:
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