Formobactin, a Novel Free Radical Scavenging and Neuronal Cell Protecting Substance from Nocardia sp.
- 1 January 1996
- journal article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 49 (9) , 839-845
- https://doi.org/10.7164/antibiotics.49.839
Abstract
Formobactin, a new free radical scavenger, was isolated from the culture of Nocardia sp. strain ND20. The structure of formobactin was determined to be a member of the nocobactin group antibiotics. Formobactin inhibited lipid peroxidation in rat brain homogenate. Formobactin also showed the activity to suppress L-glutamate toxicity in neuronal hybridoma N18-RE-105 cells.Keywords
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