Advances in childhood onset diabetes

Abstract
Childhood onset diabetes is an autoimmune disorder in the majority of cases: however, the aetiopathogenesis of several well known rare variants has recently been clarified, thereby establishing the diverse nature of the disease. These include maturity onset diabetes of the young caused by glucokinase abnormalities (MODY 2), Wolfram’s syndrome (DIDMOAD), Rabson-Mendenhall syndrome, and maternally inherited diabetes and deafness (MIDD).