A Controlled Trial of Methylphenidate in Black Adolescents
- 1 February 1988
- journal article
- research article
- Published by SAGE Publications in Clinical Pediatrics
- Vol. 27 (2) , 74-81
- https://doi.org/10.1177/000992288802700204
Abstract
The short-term effects of methylphenidate were examined on behavioral, laboratory, academic, and physiological measures in 11 black male adolescents diagnosed as having attention deficit disorder (ADD). In a double-blind, crossover design with randomized order, the subjects received placebo and each of three methylphenidate doses (0.15 mg/kg, 0.30 mg/kg, and 0.50 mg/kg) for a period of 2 weeks per medication dosage. Significant drug effects were found for the majority of measures. In general, the higher doses resulted in the most beneficial response in behavioral, academic, and laboratory measures of attention and impulsivity. However, a significant linear increase occurred in diastolic blood pressure. The results suggest that methylphenidate is an effective adjunct to the treatment of ADD in adolescents.Keywords
This publication has 16 references indexed in Scilit:
- Compliance With Pharmacological and Cognitive Treatments for Attention Deficit DisorderJournal of the American Academy of Child & Adolescent Psychiatry, 1987
- Attention deficit disorder in adolescentsClinical Psychology Review, 1986
- Methylphenidate and Children With Attention Deficit DisorderArchives of General Psychiatry, 1985
- Attention Deficit Disorder Children with or without HyperactivityClinical Pediatrics, 1985
- Hyperactive and normal children and the error, latency, and double median split scoring procedures of the matching familiar figures testJournal of School Psychology, 1980
- The hyperactive child at adolescence: Cognitive, emotional, and social functioningJournal of Abnormal Child Psychology, 1978
- Normative data on Revised Conners Parent and Teacher Rating ScalesJournal of Abnormal Child Psychology, 1978
- Do Stimulant Drugs Improve the Academic Performance of Hyperkinetic Children?Clinical Pediatrics, 1978
- Methylphenidate in Hyperkinetic Children: Differences in Dose Effects on Learning and Social BehaviorScience, 1977
- Reflection-impulsivity: The generality and dynamics of conceptual tempo.Journal of Abnormal Psychology, 1966