Heme oxygenase‐1‐derived carbon monoxide protects hearts from transplant‐associated ischemia reperfusion injury
Open Access
- 20 February 2004
- journal article
- fj express-summaries
- Published by Wiley in The FASEB Journal
- Vol. 18 (6) , 771-772
- https://doi.org/10.1096/fj.03-0921fje
Abstract
Heme oxygenase-1 (HO-1) degrades heme into iron, biliverdin, and carbon monoxide (CO). HO- 1 expression can be used therapeutically to ameliorate undesirable consequences of ischemia reperfusion inju...Keywords
Funding Information
- National Institutes of Health (RO1 HL58688, RO1 HL67040, RO1 HL‐071797)
- Pfizer
- American Heart Association (0160332U)
This publication has 53 references indexed in Scilit:
- Heavy chain ferritin acts as an anti‐apoptotic gene that protects livers from ischemia‐reperfusion injuryThe FASEB Journal, 2003
- Genetic redox preconditioning differentially modulates AP-1 and NFκB responses following cardiac ischemia/reperfusion injury and protects against necrosis and apoptosisMolecular Therapy, 2003
- Oxidative stress and neutrophil activation—the two keystones of ischemia/reperfusion injuryInternational Journal of Cardiology, 2002
- Modulation of Endothelial Cell Apoptosis by Heme Oxygenase-1-Derived Carbon MonoxideAntioxidants and Redox Signaling, 2002
- Expression of heme oxygenase-1 by endothelial cells: a protective response to injury in transplantationEmerging Therapeutic Targets, 2000
- The heme synthesis and degradation pathways: role in oxidant sensitivityFree Radical Biology & Medicine, 2000
- The ferritins: molecular properties, iron storage function and cellular regulationPublished by Elsevier ,1999
- Reperfusion injury of ischemic skeletal muscle is mediated by natural antibody and complement.The Journal of Experimental Medicine, 1996
- Involvement of lipoproteins, free radicals, and calcium in cardiovascular disease processesCardiovascular Research, 1995
- Reperfusion injury induces apoptosis in rabbit cardiomyocytes.Journal of Clinical Investigation, 1994