An Efficient Stereocontrolled Synthesis of (R)-2-Carboxy-4-(3-phosphonopropyl)piperazine [(R)-CPP]

1 February 1996

journal article
letter
Published by Georg Thieme Verlag KG in Synlett

Vol. 1996 (02) , 143-144
https://doi.org/10.1055/s-1996-5341

Abstract

The amino acid (R)-CPP (1), a selective antagonist of the NMDA receptor, is prepared directly in enantiopure form starting from L-serine and sarcosine.

Keywords

UNNATURAL Α-AMINO ACIDS
CHIRAL PIPERAZINES
CPP
NMDA ANTAGONISTS

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