Circulating immune complexes in syphilitic nephropathy. A case report.
- 1 February 1978
- journal article
- research article
- Published by BMJ in Sexually Transmitted Infections
- Vol. 54 (1) , 53-56
- https://doi.org/10.1136/sti.54.1.53
Abstract
A case of transient nephrotic syndrome caused by secondary syphilis was described. A renal biopsy was performed revealing subepithelial hump-like electron-dense deposits and fusion of epithelial foot-processes. Complement C1q-binding-activity and anti-complementarity were demonstrated in the blood, indicating the presence of circulating immune complexes. This strongly suggests that circulating immune complexes are significant in the immunopathogenesis of syphilitic nephropathy.This publication has 15 references indexed in Scilit:
- Detection Of Immune ComplexesJournal of Investigative Dermatology, 1976
- DETECTION OF CIRCULATING IMMUNE COMPLEXES IN PATHOLOGICAL HUMAN SERAThe Lancet, 1975
- Immunopathogenesis of Syphilitic GlomerulonephritisNew England Journal of Medicine, 1975
- Circulating Immune Complexes in the Serum in Systemic Lupus Erythematosus and in Carriers of Hepatitis B Antigen QUANTITATION BY BINDING TO RADIOLABELED ClqJournal of Clinical Investigation, 1974
- CIRCULATING IMMUNE COMPLEXES IN DERMATITIS HERPETIFORMISThe Lancet, 1973
- The glomerulopathy of congenital syphilis—an immune deposit diseaseThe Journal of Pediatrics, 1972
- Nephrotic syndrome: a complication of secondary syphilis.BMJ, 1971
- The nephrotic syndrome associated with secondary syphilisThe American Journal of Medicine, 1970
- Immunochemical quantitation of antigens by single radial immunodiffusionImmunochemistry, 1965
- CLINICAL NEPHROPATHIES IN EARLY SYPHILISArchives of internal medicine (1960), 1946