Oxygent™; A Novel Probe of Tissue Oxygen Tension
- 1 January 1992
- journal article
- research article
- Published by Taylor & Francis in Biomaterials, Artificial Cells and Immobilization Biotechnology
- Vol. 20 (2-4) , 929-932
- https://doi.org/10.3109/10731199209119744
Abstract
We have examined the 19F NMR spectrum and relaxation behavior of Oxygent™ (an emulsion of perfluorooctylbromide). Each of the resonances exhibits a linear relationship between spin-lattice relaxation rate and oxygen tension at constant temperature. Oxygent™ provides enhanced sensitivity to changes in oxygen tension compared with other emulsions used previously. We have used Oxygent™ to determine the oxygen tension in the liver of a mouse.Keywords
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