Bleeding During Warfarin and Aspirin Therapy in Patients With Atrial Fibrillation

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Abstract
TREATMENT WITH warfarin sodium is effective for stroke prevention in atrial fibrillation but many physicians hesitate to prescribe it to elderly patients.1-5 This reluctance may be ascribed to the associated risk for bleeding complications, to inconvenience for the patients, and to expected poor compliance in the elderly.1-5 The safety and tolerability of long-term oral anticoagulation therapy is not entirely clear in elderly patients, who have the highest risk for stroke6 and who may have an increased risk for bleeding complications.7