Expression of HLA‐A, but not of HLA‐B, in mouse‐human somatic cell hybrids carrying the region p21→pter of human chromosome 6
- 1 August 1978
- journal article
- research article
- Published by Wiley in European Journal of Immunology
- Vol. 8 (8) , 611-613
- https://doi.org/10.1002/eji.1830080814
Abstract
Mouse‐human somatic cell hy brids containing human chromosome 17 carrying the region p21→pter of human chromosome 6 and no other human chromosomes, were found to express HLA‐A but not HLA‐B. Counterselection of the hybrid cells in medium containing 5‐bromodeoxyuridine resulted in the growth of hybrid cells that have concordantly lost the expression of HLA‐A and the human translocation chromosome.This publication has 4 references indexed in Scilit:
- Assignment of the major histocompatibility complex to a region of the short arm of human chromosome 6.Proceedings of the National Academy of Sciences, 1977
- Assignment of the gene for glyoxalase I to region p21→pter of human chromosome 6Cytogenetic and Genome Research, 1977
- Human Antigen and Enzyme Markers in Man-Chinese Hamster Somatic Cell Hybrids: Evidence for Synteny Between the HL-A, PGM 3 , ME 1 , and IPO-B LociProceedings of the National Academy of Sciences, 1974
- Localization of genes on human chromosomes by studies of human-Chinese hamster somatic cell hybridsPublished by Springer Nature ,1973