Interstrand DNA crosslinks due to AP (apurinic/apyrimidinic) sites
- 5 September 1983
- journal article
- Published by Wiley in FEBS Letters
- Vol. 161 (1) , 140-144
- https://doi.org/10.1016/0014-5793(83)80747-9
Abstract
Storage of a solution of DNA containing apurinic sites, even at 4°C leads to the appearance of interstrand crosslinks. Possible biological consequences of these crosslinks, when they appear in cell DNA, are briefly discussed. Formation of interstrand crosslinks in DNA containing tritium-labelled thymine and kept in an aqueous solution might be due, at least partly, to the loss of bases by the autoirradiated DNA.Keywords
This publication has 4 references indexed in Scilit:
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- Rate of depurination of native deoxyribonucleic acidBiochemistry, 1972
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