Influence of Ouabain on Contractile Force, Resting Tension, Ca 45 Entry and Tissue Ca Content in Rat Atria
- 31 May 1963
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 12 (6) , 620-622
- https://doi.org/10.1161/01.res.12.6.620
Abstract
As was the case with guinea pig atria, ouabain induced a small but significant increment in Ca45 uptake and a drop of tissue Ca content in rat atria during the positive inotropic effect. In ouabain contractures, the uptake rate increased 87% to 170% and there was little increase in tissue Ca. Concentrations of the glycosides required to produce a positive inotropic effect and contracture in rat atria were 100- to 200-fold greater than those required in guinea pig atria.Keywords
This publication has 3 references indexed in Scilit:
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