The Protein Core of the Largest Proteoglycan Monomer of Articular Cartilage. Gel Electrophoretic Pattern and Tryptophanyl Peptide Bond Cleavage
- 1 January 1987
- journal article
- Published by Taylor & Francis in Connective Tissue Research
- Vol. 16 (4) , 377-384
- https://doi.org/10.3109/03008208709005622
Abstract
The largest proteoglycan monomer of baboon (Papio papio) articular cartilage was isolated and the protein rich core was obtained after chondroitinase AC II and keratanase digestions. On SDS-PAGE the core yielded a single band with apparent Mr of 290,000. Tryptophanyl peptide bond cleavage of the core with N-chlorosuccinimide/urea gave 4 peptides with apparent Mr of 105,000, 66,000, 62,000 and 56,000Keywords
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