Protein Microarray for Profiling Antibody Responses to Yersinia pestis Live Vaccine
Open Access
- 1 June 2005
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 73 (6) , 3734-3739
- https://doi.org/10.1128/iai.73.6.3734-3739.2005
Abstract
A protein microarray representing 149 Yersinia pestis proteins was developed to profile antibody responses in EV76-immunized rabbits. Antibodies to 50 proteins were detected. There are 11 proteins besides F1 and V antigens to which the predominant antibody response occurred, and these proteins show promise for further evaluation as candidates for subunit vaccines and/or diagnostic antigens.Keywords
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