The Lability of Thiamine in Certain Purified Rations.
- 1 August 1951
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 77 (4) , 813-816
- https://doi.org/10.3181/00379727-77-18933
Abstract
The "nervous syndrome" condition produced in rats after 10 wks. or longer on a low protein, niacin-free regimen was shown to respond to thiamine supplementation. Complete protection from the convulsions was effected when sulfasuxidine was added to the ration. Analyses showed that as much as 70% of the thiamine was destroyed in the non-sulfasuxidine ration, but very little was destroyed in the ration containing the drug. The addition of 0.2% DL-phenylalanine did not increase the thiamine requirement.Keywords
This publication has 1 reference indexed in Scilit:
- A Nervous Syndrome Produced with Phenylalanine and Methionine.Experimental Biology and Medicine, 1949