REACTION OF β-KETOSULFOXIDES WITH ALKYL GRIGNARD REAGENTS IN TETRAHYDROFURAN
- 5 March 1977
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 6 (3) , 249-252
- https://doi.org/10.1246/cl.1977.249
Abstract
The reaction of (+)-(R)-α(p-tolylsulfinyl)acetophenone(1) with alkyl Grignard reagents in tetrahydrofuran is described. When 1 was treated with 2 equiv of ethylmagnesium iodide in tetrahydrofuran at 0°C, (−)-ethyl p-tolyl sulfoxide and α(ethylsulfinyl)acetophenone were obtained.This publication has 4 references indexed in Scilit:
- Carbon-Sulfur Bond Cleavage in the Reaction of Alkyllithiums with SulfoxidesCanadian Journal of Chemistry, 1974
- Sur le mécanisme des réactions des sulfoxydesTetrahedron, 1970
- Absolute Configuration and Optical Rotatory Power of Sulfoxides and Sulfinate Esters1,2Journal of the American Chemical Society, 1965
- Reaction of Dimethyl Sulfoxide with Grignard ReagentsThe Journal of Organic Chemistry, 1961