Homovanillic acid in caudate and pre-frontal cortex following acute and chronic neuroleptic administration
- 1 January 1986
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 88 (1) , 63-65
- https://doi.org/10.1007/bf00310514
Abstract
Homovanillic acid (HVA) was measured in rat caudate and pre-frontal cortex after single and repeated doses of several types of neuroleptic drugs. Twice daily administration of low or high doses of haloperidol, fluphenazine, or (-) sulpiride resulted in greater tolerance to the initial HVA increase in caudate compared to prefrontal cortex.Keywords
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