Reversal of heart failure in thalassemia major by combined chelation therapy: a case report
- 21 December 2004
- journal article
- case report
- Published by Wiley in European Journal of Haematology
- Vol. 74 (1) , 84-85
- https://doi.org/10.1111/j.1600-0609.2004.00335.x
Abstract
In patients with thalassemia major (TM) who are non-compliant with long-term desferrioxamine (DFO) chelation, survival is limited mainly because of cardiac complications of transfusional hemosiderosis. Combined chelation therapy with DFO and deferiprone has maximized the efficacy of the therapy and reduced cardiological complications. The aim of this report is to present the results of this combination in a desperate case of heart failure.Keywords
This publication has 5 references indexed in Scilit:
- Reversal of cardiac complications in thalassemia major by long‐term intermittent daily intensive iron chelationEuropean Journal of Haematology, 2003
- Benefits and Risks of Deferiprone in Iron Overload in Thalassaemia and Other ConditionsDrug Safety, 2003
- The safety and effectiveness of deferiprone in a large‐scale, 3‐year study in Italian patientsBritish Journal of Haematology, 2002
- Lack of progressive hepatic fibrosis during long-term therapy with deferiprone in subjects with transfusion-dependent beta-thalassemiaBlood, 2002
- Combined therapy with deferiprone and desferrioxamineBritish Journal of Haematology, 1998