Tumor imaging with anti‐CEA antibody labeled 19F emulsion
- 1 September 1987
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 5 (3) , 290-295
- https://doi.org/10.1002/mrm.1910050311
Abstract
The possibility of using 19MRI for detection of tumors using a 2-T NMR system was examined in animals. Anticarcino-embryonic antigen (CEA) antibody conjugated with perfluorochemical (perfluorotributylamine, FTBA) was administered to nude mouse inoculated with LOVO, a CEA-producing human cancer cell line. Tumor imaging based on the 19F NMR was examined after excision of the tumors from nude mice (ex vivo). The imaging pattern of the tumor coincided with the antibody distribution determined immunohistologically. © 1987 Academic Press, Inc.This publication has 7 references indexed in Scilit:
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