Interferon Production by Semliki Forest Virus Inactivated with Hydroxylamine
- 1 July 1968
- journal article
- Published by Microbiology Society in Journal of General Virology
- Vol. 3 (1) , 35-42
- https://doi.org/10.1099/0022-1317-3-1-35
Abstract
Summary The inactivation of Semliki Forest virus by hydroxylamine was a first-order reaction. The ability of the partially inactivated virus to induce the production of infective virus, virus haemagglutinin, virus-induced RNA synthesis, virus-induced RNA polymerase and interferon were all inactivated with first-order kinetics. It is concluded that functional nucleic acid is essential for interferon production in this system.This publication has 0 references indexed in Scilit: