ANTIBODY RESPONSE FOLLOWING RUBELLA IMMUNIZATION ANALYZED BY HLA TYPES
- 1 January 1980
- journal article
- research article
- Published by Editorial Committee of Japanese Journal of Infectious Diseases, National Institute of Infectious Dis in Japanese Journal of Medical Science and Biology
- Vol. 33 (2) , 103-106
- https://doi.org/10.7883/yoken1952.33.103
Abstract
Possible association between HLA antigens and antibody response to rubella vaccine was examined in 71 seronegative adult females, ages 18-23, immunized with QEF vaccine. High responders (HAI [hemagglutination inhibition antigen] antibody titer .gtoreq. 1:32) with HLA-B15 were significantly higher in frequency than those without HLA-B15 (P < 0.05). Subjects with HLA-A9 had a tendency toward low immune responsiveness, including the 3 non-responders. The antibody response to rubella vaccine may be influenced by the host-genetic factors relating to HLA antigens.This publication has 8 references indexed in Scilit:
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