Group II introns in the bacterial world
Open Access
- 1 December 2000
- journal article
- review article
- Published by Wiley in Molecular Microbiology
- Vol. 38 (5) , 917-926
- https://doi.org/10.1046/j.1365-2958.2000.02197.x
Abstract
Group II introns are large catalytic RNA molecules that act as mobile genetic elements. They were initially identified in the organelle genomes of lower eukaryotes and plants, and it has been suggested that they are the progenitors of nuclear spliceosomal introns. Group II self‐splicing introns were shown to be present in bacteria in 1993, since when the various bacterial genome sequencing projects have led to a significant increase in the number of group II intron sequences present in databases. However, few of these introns have been characterized, and most were identified on the basis of their intron‐encoded protein (IEP), with little data available concerning their ribozyme/RNA structure. Their frequency in prokaryotes is also unknown. We attempt here to provide a first comprehensive review of bacterial group II introns based on recent genome sequencing data and mechanistic studies.Keywords
This publication has 52 references indexed in Scilit:
- Comparative and functional anatomy of group II catalytic introns — a reviewPublished by Elsevier ,2003
- RNA and Protein Catalysis in Group II Intron Splicing and Mobility Reactions Using Purified ComponentsBiochemistry, 1999
- Group II intron mobility in yeast mitochondria: target DNA-primed reverse transcription activity of ai1 and reverse splicing into DNA transposition sites in vitroJournal of Molecular Biology, 1998
- Group II intron endonucleases use both RNA and protein subunits for recognition of specific sequences in double-stranded DNAThe EMBO Journal, 1997
- A group II intron in a conjugative transposon from the gram-positive bacterium, Clostridium difficileGene, 1996
- Splicing of a group II intron in a functional transfer gene of Lactococcus lactisMolecular Microbiology, 1996
- Amino acid sequence motif of group I intron endonucleases is conserved in open reading frames of group II intronsTrends in Biochemical Sciences, 1994
- On the Identification of Group II Introns in Nucleotide Sequence DataJournal of Molecular Biology, 1994
- Self‐splicing group I and group II introns encode homologous (putative) DNA endonucleases of a new familyProtein Science, 1994
- Group II self-splicing introns in bacteriaNature, 1993