Studies on Bacterial Resistance to Streptomycin.
- 1 February 1947
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 64 (2) , 208-213
- https://doi.org/10.3181/00379727-64-15747
Abstract
1. Resistance to streptomycin can be induced by repeated transfer of various organisms in streptomycin containing media. 2. In the early logarithmic stage of growth, highly resistant mutants can be isolated, by chance selection, in a single transfer. 3. In most instances, acquired resistance to streptomycin is maintained. 4. Organisms resistant to streptomycin may retain their original virulence as measured by the bactericidal test. 5. The acquisition of resistance to streptomycin with the maintenance of virulence may have certain therapeutic implications.Keywords
This publication has 1 reference indexed in Scilit:
- The Role of Spontaneous Variants in the Acquisition of Streptomycin Resistance by the ShigellaeJournal of Bacteriology, 1946