Immunological features of idiopathic Addison's disease: an antibody to cells producing steroid hormones.
- 1 February 1968
- journal article
- Vol. 3 (2) , 107-17
Abstract
Antibodies to adrenocortical cells, occurring in the serum of patients with idiopathic Addison's disease, were investigated by the indirect immunofluorescence technique. With selected human adrenal tissue obtained post mortem, staining was brightest in the innermost cells of the adrenal cortex. Strongly positive sera were observed to react with all thirty specimens of adrenal tissue examined, but lipid-depleted adrenocortical tissue provided the most suitable reagent for detecting weak antibody.This publication has 14 references indexed in Scilit:
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