mTOR and cancer: many loops in one pathway

This publication has 58 references indexed in Scilit:

• Characterization of Rictor Phosphorylation Sites Reveals Direct Regulation of mTOR Complex 2 by S6K1
  Molecular and Cellular Biology, 2009
• Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
  Genes & Development, 2003
• GβL, a Positive Regulator of the Rapamycin-Sensitive Pathway Required for the Nutrient-Sensitive Interaction between Raptor and mTOR
  Molecular Cell, 2003
• PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms
  Published by Elsevier ,2003
• Two TOR Complexes, Only One of which Is Rapamycin Sensitive, Have Distinct Roles in Cell Growth Control
  Molecular Cell, 2002
• Identification of the Tuberous Sclerosis Complex-2 Tumor Suppressor Gene Product Tuberin as a Target of the Phosphoinositide 3-Kinase/Akt Pathway
  Published by Elsevier ,2002
• Raptor, a Binding Partner of Target of Rapamycin (TOR), Mediates TOR Action
  Cell, 2002
• mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery
  Cell, 2002
• Role of mTOR in the degradation of IRS‐1: Regulation of PP2A activity
  Journal of Cellular Biochemistry, 2002
• A Rapamycin-Sensitive Pathway Down-Regulates Insulin Signaling via Phosphorylation and Proteasomal Degradation of Insulin Receptor Substrate-1
  Molecular Endocrinology, 2000