Malaria in Man

29 June 1963

journal article
research article
Published by American Medical Association (AMA)

Vol. 184 (13) , 1018-1020
https://doi.org/10.1001/jama.1963.73700260001010

Abstract

WE KNOW THAT man acts as the normal host for four species of human malaria:Plasmodium vivax, P falciparum, P malariae, andP ovale. The possibility of nonhuman reservoirs was not seriously considered until Eyles et al¹demonstrated a fifth species ofPlasmodiumtransmissible to man, the B strain ofP cynomolgi, normally a parasite of monkeys. Four accidental infections by this simian malaria occurred amongst laboratory workers in the US between April and July of 1960, making it apparent that the B strain ofP cynomolgiwas capable of producing malaria in man.² Initial studies with inmate volunteers infected with this parasite were carried out by Dr. Henry Beye and his associates³at the US Federal Penitentiary in Atlanta, with emphasis placed on clinical and parasitological observations. Additional clinical and physiological responses in inmate volunteers infected with this B strain ofP cynomolgiand the comparison

Keywords

This publication has 0 references indexed in Scilit: