Complete assignment of the 1H NMR spectrum of a synthetic zinc finger from Xfin Sequential resonance assignments and secondary structure
- 28 August 1989
- journal article
- Published by Wiley in FEBS Letters
- Vol. 254 (1-2) , 159-164
- https://doi.org/10.1016/0014-5793(89)81030-0
Abstract
A 25‐residue synthetic peptide corresponding to zinc finger 31 of the Xenopus protein Xfin adopts a compact, folded conformation in the presence of zinc. Complete 1H resonance assignments have been made. The peptide contains a helix, beginning as an α‐helix and ending as a 310‐helix, that extends from residue 12 to 23. Several positively charged and polar residues located on this helix are likely to be involved in interactions with DNA. Residues 1–10 appear to adopt a hairpin‐like structure.Keywords
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