Considerations of oxygen-hemoglobin equilibrium in the physiological state
- 1 January 1961
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 200 (1) , 135-142
- https://doi.org/10.1152/ajplegacy.1961.200.1.135
Abstract
A formulation is presented, which applies to the oxygen-hemoglobin equilibrium under physiological conditions. This formulation fits with excellent accuracy the experimental data obtained by various authors in man and in several animal species. The marked difference in the comportment of intracellular and dilute hemoglobin is emphasized. It is indicated that Adair's four compounds hypothesis does not apply in its simplest form to intracellular hemoglobin, unless different values for different O2 partial pressures are given to the association ‘coefficients’ and in particular to that of the fourth hemoglobin compound.Keywords
This publication has 2 references indexed in Scilit:
- Dielectric Properties of Hemoglobin. I. Studies at 1 MegacycleJournal of the American Chemical Society, 1956
- The Oxygen Equilibrium of Hemoglobin and Its Structural InterpretationProceedings of the National Academy of Sciences, 1935