Neuron-Specific Enolase in Comatose Children
- 1 February 1988
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Pediatrics & Adolescent Medicine
- Vol. 142 (2) , 173-174
- https://doi.org/10.1001/archpedi.1988.02150020075032
Abstract
• Sequential examination of neuronspecific enolase in cerebrospinal fluid and serum was performed in 20 comatose children with acute encephalitis, acute encephalopathy, or Reye's syndrome. Neuron-specific enolase activities corresponded to the degree of brain damage. As neuron-specific enolase levels increased to greater than 80 ng/mL, patients had more severe impairment or died. Neuron-specific enolase may be a useful marker for evaluating the degree of neuronal damage and prognosis. (AJDC 1988;142:173-174)This publication has 3 references indexed in Scilit:
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- Release of neuron specific enolase (NSE) in cerebrospinal fluid following experimental lesions of the rat brainNeurochemistry International, 1983
- Human 14‐3‐3 Protein: Radioimmunoassay, Tissue Distribution, and Cerebrospinal Fluid Levels in Patients with Neurological DisordersJournal of Neurochemistry, 1982